Potential interaction applies to mycophenolate mofetil. Cholestyramine binds bile acids and reduces mycophenolic acid exposure. Applies only to oral form of both agents. Neutropenia or febrile neutropenia incidence were increased when trastuzumab was coadministered with myelosuppressive chemotherapy. Use Caution/Monitor. Immediately after surgery, your abdomen will be slightly bloated so you may have trouble fitting into your regular clothes. Contraindicated. Depression in women: 5 things you should know. This image is not<\/b> licensed under the Creative Commons license applied to text content and some other images posted to the wikiHow website. Avoid or Use Alternate Drug. Manage and view all your plans together even plans in different states. Use Caution/Monitor. Use Caution/Monitor. Both drugs can cause metabolic acidosis. bendroflumethiazide will increase the level or effect of mycophenolate by acidic (anionic) drug competition for renal tubular clearance. Use Caution/Monitor. Lewis G, et al. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Depression in women: Understanding the gender gap, Begin Exploring Women's Health Solutions at Mayo Clinic Store, Newsletter: Mayo Clinic Health Letter Digital Edition, Book: Mayo Clinic Family Health Book, 5th Edition, Understanding the difference between dementia types. Last Updated: July 28, 2022 Use Caution/Monitor. mycophenolate, tisagenlecleucel. Use Caution/Monitor. wikiHow, Inc. is the copyright holder of this image under U.S. and international copyright laws. If placing the infant on his or her stomach does not solve the problem, other treatments aimed at keeping the upper airway open may be recommended. There are also exercises you can do at home (or in front of your computer at work) to gently stretch your neck muscles. a kind of stomach cancer called gastric or gastroesophageal junction (GEJ) adenocarcinoma. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. WebAll classifieds - Veux-Veux-Pas, free classified ads Website. This article was medically reviewed by Erik Kramer, DO, MPH. Nurse: KEYTRUDA helps your own immune system do what its designed to do: find and fight cancer. Tell your health care provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Theyll cause the area to be red, painful, and even hot to the touch. Monitor Closely (1)mefenamic acid will increase the level or effect of mycophenolate by acidic (anionic) drug competition for renal tubular clearance. Avoid or Use Alternate Drug. Use Caution/Monitor. Serious - Use Alternative (1)muromonab CD3 and mycophenolate both increase immunosuppressive effects; risk of infection. Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. https://doi.org/10.1371/journal.pone.0198804. information submitted for this request. Serious - Use Alternative (1)mycophenolate decreases effects of diphtheria & tetanus toxoids/ acellular pertussis vaccine by pharmacodynamic antagonism. Your doctor may order a pregnancy test before starting this medication, after 8 to 10 days on treatment, and during routine follow-up visits. Mycophenolate may harm an unborn baby. Insulin resistance and type 2 diabetes Cirrhosis causes resistance to insulin-a hormone produced by the pancreas that enables the body to use glucose as energy. Applies only to oral form of both agents. You should always contact your doctor or other qualified healthcare professional before starting, changing, or stopping any kind of health treatment. Use Caution/Monitor. Either increases toxicity of the other by immunosuppressive effects; risk of infection. Applies only to oral form of both agents. Immune response to vaccine may be decreased in immunocompromised individuals. sodium zirconium cyclosilicate will decrease the level or effect of mycophenolate by increasing gastric pH. Dr. Mark Truty (surgery, MN) better outcomes with chemo. mycophenolate decreases effects of yellow fever vaccine by pharmacodynamic antagonism. you have received chemotherapy, and it did not work or is no longer working. mycophenolate decreases effects of rotavirus oral vaccine, live by pharmacodynamic antagonism. All rights reserved. trastuzumab deruxtecan, mycophenolate. Minor (1)mycophenolate decreases effects of estradiol by unknown mechanism. Ask your pharmacist for more details.Do not change brands or forms of mycophenolate unless directed by your doctor. Do not donate sperm while using mycophenolate and for 90 days after stopping this drug.Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the tablets or powder from the capsules.Tell your doctor if you are pregnant or plan to become pregnant. Mayo Clinic. Avoid or Use Alternate Drug. Information last revised April 2022. There is a problem with Minor/Significance Unknown. Minor/Significance Unknown. Clinical significance unclear. Immunosuppressive therapies may reduce the effectiveness of zoster vaccine recombinant. Contraindicated. Use Caution/Monitor. Immunosuppressants also increase risk of infection with concomitant live vaccines. Serious - Use Alternative (1)mycophenolate decreases effects of pneumococcal vaccine heptavalent by pharmacodynamic antagonism. Use Caution/Monitor. As you approach your late 30s, your ovaries start making less estrogen and progesterone the hormones that regulate menstruation and your fertility declines. They may also need to delay or completely stop treatment with KEYTRUDA if you have severe side effects. Minor (1)mycophenolate decreases effects of conjugated estrogens by unknown mechanism. Use Caution/Monitor. information and will only use or disclose that information as set forth in our notice of Some children may also require speech therapy following cleft palate repair. Avoid or Use Alternate Drug. prescription products. If you think you're depressed, don't hesitate to seek help. It's diagnosed after you've gone 12 months without a menstrual period. Antidepressants: Selecting one that's right for you. Well, sometimes one particular immune system cell known as a T cell needs help to recognize cancer. References. Modify Therapy/Monitor Closely. What breastfeeding positions might work best for you? They may re-apply the wrap at each treatment. Compare formulary status to other drugs in the same class. It may be used with the chemotherapy medicines pemetrexed and a platinum as your first treatment when your lung cancer has spread, It may be used with the chemotherapy medicines carboplatin and either paclitaxel or paclitaxel. Monitor Closely (1)sulindac will increase the level or effect of mycophenolate by acidic (anionic) drug competition for renal tubular clearance. Some of this excess overnight swelling will disappear once you get up and start moving around. Wild yam. The fan theories revolving around Jun Kazama were true, after all. Applies to didanosine chewable tablets and powder for oral solution; administer 2 hr before or several hours after didanosine oral solution or chewable tablet administration. Contraindicated (1)cholestyramine decreases levels of mycophenolate by inhibition of GI absorption. Use Caution/Monitor. Applies only to oral form of both agents. Comment: Caution should be taken in patients on concomitant immunosuppressants or with impaired immune systems because of increased risk for serious infections. health information, we will treat all of that information as protected health nirmatrelvir/ritonavir, mycophenolate. Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Monitor. mycophenolate increases and maitake decreases immunosuppressive effects; risk of infection. Immunosuppressives may diminish therapeutic effects of vaccines and increase risk of adverse effects (increased risk of infection). Immunosuppressive therapies, including irradiation, antimetabolites, alkylating agents, cytotoxic drugs, and corticosteroids (used in greater than physiologic doses), may reduce the immune responses to vaccines. WebBabies born with Pierre Robin sequence commonly experience trouble breathing and feeding early on, resulting from the tongues position, smaller jaw size and the cleft palate formation. Contraindicated. Contraindicated. Monitor Closely (1)ceftibuten will increase the level or effect of mycophenolate by acidic (anionic) drug competition for renal tubular clearance. if your cancer is shown by a laboratory test to be microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR). Infants with minor degrees of Pierre Robin sequence can learn to feed using specially adapted nipples and bottles. Use Caution/Monitor. Applies only to oral form of both agents. KEYTRUDA is a medicine that may treat certain cancers by working with your immune system. Frequent breastfeeding on both breasts is recommended to avoid or minimize engorgement. Public healthcare system of the UK Surgery to remove your ovaries causes immediate menopause. Immunosuppressants also increase risk of infection with concomitant live vaccines. The 2017 hormone therapy position statement of The North American Menopause Society. mycophenolate decreases effects of pneumococcal vaccine 13-valent by pharmacodynamic antagonism. Colestipol binds bile acids and reduces mycophenolic acid exposure. chlorothiazide will increase the level or effect of mycophenolate by acidic (anionic) drug competition for renal tubular clearance. X mesalamine will increase the level or effect of mycophenolate by acidic (anionic) drug competition for renal tubular clearance. privacy practices. Applies only to oral form of both agents. a kind of bladder and urinary tract cancer called urothelial carcinoma. Use Caution/Monitor. Use Caution/Monitor. Your list will be saved and can be edited at any time. Minor/Significance Unknown. Monitor Closely (1)trastuzumab deruxtecan, mycophenolate. If you're planning a cesarean delivery or you want to be prepared in case you need to have a C-section, you might have questions about the recovery process. Applies only to oral form of both agents. Always ask your health care professional for complete information about this product and your specific health needs. Contraindicated. Applies only to oral form of both agents. Welt CK. Primary Care Companion for CNS Disorders. mycophenolate, axicabtagene ciloleucel. Use Caution/Monitor. Interaction only with oral iron administration. Remember, depression is both common and treatable. Natural Medicines. didanosine will decrease the level or effect of mycophenolate by increasing gastric pH. Serious - Use Alternative (1)mycophenolate decreases effects of influenza virus vaccine quadrivalent, intranasal by pharmacodynamic antagonism. wikiHow, Inc. is the copyright holder of this image under U.S. and international copyright laws. Applies only to oral form of both agents. Use Caution/Monitor. You are encouraged to report negative side effects of prescription drugs to the FDA. mycophenolate, brexucabtagene autoleucel. then wake up after hrs of sleeping with excruciating pain in my upper left chest area. Surgery, otherwise known as General Surgery is a surgical specialty that focuses on alimentary canal [GI Tract] and abdominal contents including the esophagus, stomach, small intestine, large intestine, liver, pancreas, gallbladder, appendix and bile ducts, and often the thyroid gland. Intestinal problems: diarrhea (loose stools) or more frequent bowel movements than usual; stools that are black, tarry, sticky, or have blood or mucus; or severe stomach-area (abdomen) pain or tenderness. https://www.psychiatrist.com/pcc/article/Pages/2015/v17n01/14r01721.aspx. polysaccharide iron decreases levels of mycophenolate by inhibition of GI absorption. Interaction only with oral iron administration. Either increases levels of the other by decreasing renal clearance. Migraine treatment: Can antidepressants help? Seek help if you have any signs and symptoms of depression, such as: Not sure how to get treatment? Use Caution/Monitor. Effect of interaction is not clear, use caution. Bachmann G, et al. Women are nearly twice as likely as men to be diagnosed with depression. iron dextran complex decreases levels of mycophenolate by inhibition of GI absorption. The KEY+YOU Patient Support Program is designed to offer educational resources to help with the practical and emotional challenges of cancer. KEYTRUDA is not chemotherapy or radiation therapyit is an immunotherapy and it works with your immune system to help fight cancer. mycophenolate decreases effects of hepatitis A vaccine inactivated by pharmacodynamic antagonism. choline magnesium trisalicylate will increase the level or effect of mycophenolate by acidic (anionic) drug competition for renal tubular clearance. While this sounds pretty scary, try not to worry. Centers for Disease Control and Prevention. This site is intended only for residents of the United States, its territories, and Puerto Rico. Avoid or Use Alternate Drug. alefacept and mycophenolate both increase immunosuppressive effects; risk of infection. mycophenolate decreases effects of varicella virus vaccine live by pharmacodynamic antagonism. Speak to your doctor for specific Avoid or Use Alternate Drug. 2014; doi:10.1097/01.AOG.0000441353.20693.78. This can happen during or after treatment and may be severe and lead to death. Men with female partners of childbearing age should use reliable forms of birth control while using this medication and for 3 months after the last dose. mycophenolate, ciltacabtagene autoleucel. Orthodontists, pediatric dentists and craniofacial surgeons should work together to monitor dental development. Contraindicated. Youll probably notice a major improvement by around 2 weeks after surgery, at which point the swelling should be down by about 75%. dichlorphenamide and mycophenolate both decrease serum potassium. Polygamist leader and 'prophet' had 20 wives, including minors: Affidavit. Use Caution/Monitor. In press. Antidepressants and weight gain: What causes it? Either increases effects of the other by pharmacodynamic synergism. salsalate will increase the level or effect of mycophenolate by acidic (anionic) drug competition for renal tubular clearance. Continue getting these appointments during and after menopause. Patients prescribed KEYTRUDA for an approved indication can receive phone support, e-mails, and online activities. Immunosuppressants also increase risk of infection with concomitant live vaccines. Applies only to oral form of both agents. Use Caution/Monitor. Use Caution/Monitor. This information is not individual medical advice and does not substitute for the advice of your health care professional. Tell your doctor about all your medical conditions, including immune system problems, or if youve had an organ transplant, had or plan to have a stem cell transplant, or have had radiation to your chest area or a nervous system condition. mycophenolate decreases effects of zoster vaccine live by pharmacodynamic antagonism. Surgery that removes the ovaries (oophorectomy). If youve recently been prescribed KEYTRUDA, the quick start guide for KEYTRUDA gives you step-by-step information to help you prepare for your treatment, become familiar with possible side effects, and more. Minor/Significance Unknown. Contraindicated. Avoid or Use Alternate Drug. Avoid or Use Alternate Drug. restrictions. Either increases toxicity of the other by immunosuppressive effects; risk of infection. Did the definition of Alzheimer's disease change? https://www.uptodate.com/contents/search. Avoid or Use Alternate Drug. Coadministration with immunosuppressive therapies may increase the risk of additive immune effects during therapy and in the weeks following administration. metolazone will increase the level or effect of mycophenolate by acidic (anionic) drug competition for renal tubular clearance. Use Caution/Monitor. Caution should be taken in patients on concomitant immunosuppressants or with impaired immune systems because of increased risk for serious infections. Monitor Closely (1)hydroxyurea, mycophenolate. Use Caution/Monitor. Use Caution/Monitor. Symptoms of an abruption usually include bleeding and abdominal pain. Monitor Closely (1)oxaprozin will increase the level or effect of mycophenolate by acidic (anionic) drug competition for renal tubular clearance. Use Caution/Monitor.dichlorphenamide, mycophenolate. Individuals with altered immunocompetence may have reduced immune responses to the vaccine. Use Caution/Monitor. Heart disease facts. Use Caution/Monitor. Serious - Use Alternative (1)mycophenolate and sirolimus both increase immunosuppressive effects; risk of infection. nafcillin, mycophenolate. After delivery, you'll experience hair loss up to five months after delivery. Serious - Use Alternative (1)ferrous fumarate decreases levels of mycophenolate by inhibition of GI absorption. Monitor Closely (1)acyclovir will increase the level or effect of mycophenolate by acidic (anionic) drug competition for renal tubular clearance. Immunosuppressants also increase risk of infection with concomitant live vaccines. Avoid or Use Alternate Drug. PlosOne. Monitor Closely (1)mycophenolate decreases effects of dengue vaccine by immunosuppressive effects; risk of infection. leflunomide and mycophenolate both increase immunosuppressive effects; risk of infection. iron sucrose decreases levels of mycophenolate by inhibition of GI absorption. sulindac will increase the level or effect of mycophenolate by acidic (anionic) drug competition for renal tubular clearance. Contraindicated. Enteric coated mycophenolate sodium formulation is less sensitive to this interaction. If you're not breastfeeding, wear a supportive bra, such as a sports bra. Abscess: A pus-filled cavity; an abscess in the breast of a nursing woman can result from untreated mastitis, or breast infection. This article has been viewed 27,383 times. Potential interaction applies to mycophenolate mofetil. Frequently asked questions. Use Caution/Monitor. Use Caution/Monitor. Avoid or Use Alternate Drug. Depression risk may also rise during early menopause or after menopause both times when estrogen levels are significantly reduced. NOTES: Do not share this medication with others.Lab and/or medical tests (such as blood counts, drug levels, kidney function, pregnancy test) should be done while you are taking this medication. Comment: Combination may increase risk of immunosuppression. For comfort, wear lose fitting clothing such as sweatpants or other pants with elastic (not button) waist bands. Go to source. KEYTRUDA can harm your unborn baby. ketoprofen will increase the level or effect of mycophenolate by acidic (anionic) drug competition for renal tubular clearance. After menopause, your risk of certain medical conditions increases. Use Caution/Monitor. Monitor Closely (1)mycophenolate increases and astragalus decreases immunosuppressive effects; risk of infection. telmisartan will decrease the level or effect of mycophenolate by Other (see comment). Avoid vaccination during chemotherapy or radiation therapy if possible because antibody response might be suboptimal. Avoid or Use Alternate Drug. If you are having trouble sleeping, talk to your doctor. Enteric coated mycophenolate sodium formulation is less sensitive to this interaction. mycophenolate decreases effects of Japanese encephalitis virus vaccine by pharmacodynamic antagonism. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. The swelling will typically increase within the first 48 hours after surgery, then start to go down after about a week. https://www.acog.org/Patients/FAQs/Cesarean-Birth-C-Section. Monitor Closely (1)mycophenolate decreases effects of haemophilus influenzae type b vaccine by pharmacodynamic antagonism. Puberty is often associated with other experiences that can play a role in depression, such as: After puberty, depression rates are higher in females than in males. Monitor Closely (1)lomustine and mycophenolate both increase immunosuppressive effects; risk of infection. This document does not contain all possible drug interactions. Immunosuppressants also increase risk of infection with concomitant live vaccines. Prophylaxis of organ rejection in patients receiving allogeneic renal transplants; use concomitantly with cyclosporine and corticosteroids, Mycophenolate mofetil (MMF): 1 g PO/IV q12hr, infused over 2 hours, Prophylaxis of organ rejection in patients receiving allogeneic cardiac transplants; use concomitantly with cyclosporine and corticosteroids, MMF: 1.5 g PO/IV q12hr, infused over 2 hours, Prophylaxis of organ rejection in patients receiving allogeneic hepatic transplants; use concomitantly with cyclosporine and corticosteroids, MMF (IV): 1 g q12hr; infused over 2 hours, Induction therapy for lupus nephritis (MMF), Induction: 1 g PO q12hr with a glucocorticoid or 2-3 g for 6 months with glucocorticoids, Maintenance: 0.5-3 g/day or 1 g PO q12hr or 1-2 g daily, Administer with initial IV corticosteroid pulse for 3 days, then prednisone 0.5-1 mg/kg/day PO; not to exceed 10 mg/day; after a few weeks, prednisone may be tapered to lowest effective dose, Indicated for prophylaxis of organ rejection in combination with other immunosuppressive agents in patients receiving allogeneic heart transplants, Indicated for prophylaxis of organ rejection in combination with other immunosuppressive drugs in children aged 3 months receiving allogeneic heart transplants, Suspension: 600 mg/m2 PO q12hr; if tolerated, may increase dose to maintenance of 900 mg/m2 BID (not to exceed 3 g/day), Capsules; BSA 1.25 to <1.5 m2: 750 mg capsule PO q12hr initially; may increase maintenance dose, not to exceed 3 g/day, Capsules or tablets; BSA 1.5 m2: 1 g capsule/tablet PO q12hr initially; may increase maintenance dose, not to exceed 3 g/day, Indicated for prophylaxis of organ rejection in combination with other immunosuppressive drugs in children aged 3 months receiving allogeneic liver transplants. Rockville, Md. Use Caution/Monitor. and formulary information changes. In: Williams Obstetrics. Serious - Use Alternative (1)mycophenolate decreases effects of rabies vaccine chick embryo cell derived by pharmacodynamic antagonism. Sexual function. Immunosuppressants also increase risk of infection with concomitant live vaccines. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Serious - Use Alternative (1)antithymocyte globulin rabbit and mycophenolate both increase immunosuppressive effects; risk of infection. https://www.womenshealth.gov/menopause/menopause-and-your-health. Use Caution/Monitor. Monitor Closely (1)famotidine will decrease the level or effect of mycophenolate by increasing gastric pH. rose hips decreases levels of mycophenolate by inhibition of GI absorption. Monitor Closely (1)mycophenolate increases effects of fingolimod by immunosuppressive effects; risk of infection. Use Caution/Monitor. Monitor Closely (1)sulfasalazine will increase the level or effect of mycophenolate by acidic (anionic) drug competition for renal tubular clearance. While the condition is equally common in males and females, there is a higher incidence among twins. wikiHow, Inc. is the copyright holder of this image under U.S. and international copyright laws. . has progressed following treatment, and you have no satisfactory treatment options. You may opt-out of email communications at any time by clicking on Accessed Jan. 29, 2020. Vaginal dryness from decreased moisture production and loss of elasticity can cause discomfort and slight bleeding during sexual intercourse. Use Caution/Monitor. Most likely, you'll experience some irregularity in your periods before they end. Minor (1)mycophenolate decreases effects of estrogens esterified by unknown mechanism. Accessed Jan. 29, 2020. Avoid or Use Alternate Drug. mycophenolate decreases effects of influenza virus vaccine quadrivalent, adjuvanted by pharmacodynamic antagonism. Contraindicated. Coadministration with other other myelosuppressive anticancer agents, including DNA damaging agents, may potentiate and prolongate the myelosuppressive toxicity. You can begin breastfeeding almost immediately after the C-section. Serious - Use Alternative (1)mycophenolate, ciltacabtagene autoleucel. Avoid or Use Alternate Drug. Immunosuppressants also increase risk of infection with concomitant live vaccines. When using mycophenolate, men and women of childbearing age must use reliable forms of birth control. Use Caution/Monitor. If your child has Pierre Robin sequence, you can expect treatment to come in stages. The American College of Obstetricians and Gynecologists recommends that postpartum care be an ongoing process rather than just a single visit after your delivery. Either increases effects of the other by immunosuppressive effects; risk of infection. Depression in women Understanding the gender gap, Advertising and sponsorship opportunities, Increasing pressure to achieve in school, sports or other areas of life, Lifestyle or work changes or other life stressors, Previous episodes of depression, postpartum depression or PMDD, Stopping use of antidepressant medications, Low self-esteem or feeling like you're a bad mom, Trouble sleeping, even when your baby is sleeping, Major hormonal fluctuations that influence mood, The responsibility of caring for a newborn, Predisposition to mood and anxiety disorders, Weight gain or a higher body mass index (BMI), Menopause caused by surgical removal of the ovaries, Ongoing feelings of sadness, guilt or hopelessness, Loss of interest in things you once enjoyed, Significant changes in your sleep pattern, such as trouble falling or staying asleep or sleeping too much, Fatigue or unexplained pain or other physical symptoms without an apparent cause, Problems concentrating or remembering things, Changes in appetite leading to significant weight loss or weight gain, Feeling as though life isn't worth living, or having thoughts of suicide. Monitor Closely (1)mycophenolate decreases effects of sipuleucel-T by pharmacodynamic antagonism. Serious - Use Alternative (1)ticarcillin, mycophenolate. If you experience severe mood swings, loss of appetite, overwhelming fatigue and lack of joy in life shortly after childbirth, you might have postpartum depression. In general, administer drugs at least 2 hr before or after sodium zirconium cyclosilicate. isavuconazonium sulfate will increase the level or effect of mycophenolate by Other (see comment). 2 hours ago. Contact your health care provider if you think you might be depressed, especially if your signs and symptoms don't fade on their own, you have trouble caring for your baby or completing daily tasks, or you have thoughts of harming yourself or your baby. Immunosuppressants also increase risk of infection with concomitant live vaccines. This image is not<\/b> licensed under the Creative Commons license applied to text content and some other images posted to the wikiHow website. Serious - Use Alternative (1)mycophenolate decreases effects of measles mumps and rubella vaccine, live by pharmacodynamic antagonism. mycophenolate increases effects of fingolimod by immunosuppressive effects; risk of infection. Dramatic hormonal changes occur during pregnancy, and these can affect mood. If your facial swelling increases or doesnt improve after you start steroids, talk to your doctor or surgeon about whether this might be a side effect of the steroids. Effect of interaction is not clear, use caution. Serious - Use Alternative (1)mycophenolate decreases effects of smallpox (vaccinia) vaccine, live by pharmacodynamic antagonism. {"smallUrl":"https:\/\/www.wikihow.com\/images\/thumb\/b\/b9\/Reduce-Facial-Swelling-After-Surgery-Step-1.jpg\/v4-460px-Reduce-Facial-Swelling-After-Surgery-Step-1.jpg","bigUrl":"\/images\/thumb\/b\/b9\/Reduce-Facial-Swelling-After-Surgery-Step-1.jpg\/aid11646169-v4-728px-Reduce-Facial-Swelling-After-Surgery-Step-1.jpg","smallWidth":460,"smallHeight":345,"bigWidth":728,"bigHeight":546,"licensing":"